Special Synthetic Request

Customized synthesis, separation and purification of high optical purity of chiral compounds and standards based on Medinoah’s powerful chemical synthesis capabilities and proven analytical platform
-- High efficiency, high optical purity and chiral separation
Preparation of chiral compounds by chemical methods, column chromatography and/or Supercritical fluid chromatography (SFC)
-- Chiral synthesis
Synthesis of chiral molecules is based on the structure of target molecules

Medinoah’s ADChem platform provides a reasonable design, synthesis, scale-up and GMP production for linkers, payloads, and payload-linker conjugates, available in 1 mg to 100 g.
Chromatographic purification methods such as SEC, HIC, IEX, UF/DF, etc.
Characterization methods such as UV, SEC, HIC, RP, LC-MS, SEC-MALL, endotoxin analysis, etc.
Multi-mode coupling technology to meet ADC drug development needs

Enrichment, separation, purification, structural identification, structural confirmation and analytical characterization of drug impurities
Synthesis of target impurities
Synthesis and modification of literature reported compounds
Currently, we have more than 100 catalog compound libraries of off-patent drug impurities, with continuous effort to expand according to the development of off-patent drugs, in stock and/or customized synthesis.